Parnate, Nardil & Marplan: a cure-all?
Three older antidepressants — MAOIs, or monoamine oxidase inhibitors — are among the most effective treatments for depression and anxiety disorders that have resisted other treatments. Yet they are surrounded by fears and have become difficult to obtain. This site separates real risks from misconceptions, and explains how to access them in your country.
Why MAOIs work differently from all other antidepressants (SSRIs, SNRIs and tricyclics) — and what that difference changes in practice.
Understand →Fear of tyramine, the myth of “interactions with everything,” a reputation for danger… what is fact and what is misconception.
Explore →The one real dietary constraint, demystified: a clear, searchable list, plus the warning signs to know.
View →The drug-related counterpart to the tyramine diet: the short list to avoid, over-the-counter pitfalls, safety intervals and everything that remains compatible.
Explore →Parnate, Nardil and Marplan: what is (or is not) marketed in France, Belgium, Switzerland and Canada, and the actual steps in each country.
Explore →It can be difficult to mention a class of medicines that your doctor may know only superficially. We can help.
Explore →This website provides general information and cannot replace advice from a physician or pharmacist. Do not make any treatment decision without a healthcare professional. MAOIs involve real precautions — dietary and, above all, drug-interaction precautions — which are detailed on the relevant pages.